My research activities for the next five years will focus on the following areas:
1 – Evolution of the digestive system and adaptive homeostasis in sponges with a special attention to carnivorous species (approaches : molecular and cellular biology, transcriptomics. Main model : Lycopodina hypogea)
2 – Epithelio/mesenchymatous transition, transdifferentiation and epigenetic regulation at the root of metazoans (approaches: molecular and cellular biology, transcriptomics. Models: Lycopodina hypogea, Oscarella lobularis, Halisarca dujardini)
3 – Study of the « topological invariance » of non-proliferative, proliferative and hyper-proliferative epithelial monolayers with spherical, planar or random geometries (approaches: cell biology, mathematical physics. Models: Tunicates, Drosophila, COS cells, human cancerous (HeLa) and non-cancerous (hCerEpic) epithelial cells).
4 – Physiopathology of transmissible cancer in mussels (approaches : cellular and molecular ecophysiology. Models: Mytilus galloprovincialis, edulis and trossulus).
At the same time, I teach cell biology from L2 to M1 and the history of biology in L3.