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Marine Combe


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My activity

My work focuses on the ecological and biological mechanisms behind zoonotic pathogen emergence. I focus on the genetic diversity of strains available in the aquatic environment, the selection of virulent strains and their transmission between animals and humans in a context of global changes, including deforestation, urbanization, climate changes, aquaculture intensification and biological invasions. To develop these OneHealth/EcoHealth approaches of infectious disease emergence I use diverse tools such as eDNA, genomics and biogeography.
My researches are organized around several biodiversity-health related projects:
(i) the emergence of zoonotic human infectious diseases such as Buruli ulcer caused by environmental mycobacteria in French Guiana and Côte d’Ivoire (ANR PRIME, CEBA MicroBIOMES)
(ii) the COVID-19/SARS-CoV-2 epidemiological dynamics in wastewater in French Guiana (ANR EPI-COV)
(iii) The worldwide emergence of fungal pathogens due to biological invasions in freshwater aquacultures and wild ecosystems in Asia and Mediterranean (ROSETTA)
(iv) The emergence of fish pathogens and antimicrobial resistance in freshwater aquacultures in Cambodia and Vietnam (FSPI AquaCam)

Keywords :

Emerging infectious diseases – OneHealth/EcoHealth – Disease ecology – Biodiversity – Genetic diversity